Characterisation of diffusion-weighted magnetic resonance imaging of focal hepatic lesions
e-Poster: C-016
Congress: ECR 2009
Type: Scientific Exhibit
Topic: Abdominal and Gastrointestinal / Abdominal Viscera (Solid Organs) / Liver
Authors: , L. Gorospe Sarasus, M. Valle de Frutos, T. Gómez San Roman, A. Palomar A. Pinardo Zabala Estrada, V.R. Lara Mazenett; Puertollano/ES
MeSH: Diffusion Magnetic Resonance Imaging [E01.370.350.500.150]
Keywords: Diffusion-weighted MRI, Focal lesion hepatics
1. Purpose
Diffusion-weighted magnetic resonance imagign(DWMRI) is a new technique of magnetic resonance imaging (MRI) at the level of molecular movements and can relect the functions and structures of the body without trauma. It has been used to diagnose diseases in the central nervous system(1). Our purpose is to correlate focal hepatic lesions, our characteritation with diffusion-weighted.
2. Methods and Materials
This study was performed in 38 patiens with focal hepatic lesins(30 women and 8 men, aged 25-88 years, mean 52.37 years), including hepatocellular carcinomas, hepatic metastases, cholangiocarcinoma,cavernoys hemangiomas, and hepatic cysts.
The criteria for selecting the patients were as follows:
-The diagnosis of all cases of hepatocellular carcinoma was confirmed by alfa fetal protein, clinical data, ultrasound, CT or/and MR imagin, and pathology.
-All cases of hepatic metastasis of primary malignant tumor were high suspicion performed by different sequences.
-The diagnosis of all cases of cavernous hemangioma and hepatic cyst was confirmed by clinical data, ultrasound, CT or/and MR imagin, and follow-up observation.
The standars of measurement of signal intensities in hepatic lesions on DW-MRI were as follow: the largest diameter of lesions was measured, two regins of interest in each lesion were marked off and measured, the regions of blood vessels and artifacts were rejected, the edges of parenchyma in the lesion were measure, when apparent necrosis was present, and regions of interest should involve parenchyma an the diameter of it should be longer than 1 cm, the same area of the section should be chosen for the measurement of different sequences, the signal intensity of each ROI was measured thrice and a mean valy of SI was acquired for ADC calculation.
DWMRI was performed by 1.5 T MR with a body coil (Philips). All data were measured in control console. All lesions were scanned with spin-echo (SE) T1WI and fast SE T2WI in the axial and coronal plane.
The imaging parameters of DWMRI with SE-echo planar imaging (EPI) sequence were set as follows: repetition time ms/echo time ms: 10 000/90; matrix: 128×128; field of view
3. Results
The hepatic MRI was performe in 30 patients with 51 focal hepatic lesion (36 women, 15 men, aged 36-65 yearse, mean 46,8), including 1 hepatocellular carcinomas, 1 cholangiocarcinoma periferic, 11 hepatic metastasis, 12 cavernous hemangiomas, 18 hetic cysts, 8 indeterminates lesions focals hepatics.
The diameter of the lesions was 17,6 cm
We measured the highest b value (b=600 mm2/s) con DWMRI in the focal hepatic lesions. The ADC values in hepatic cyst were signifcantly higher than others, with t-test value of 2.1243 (p<0.01). No significant difference was demonstrated between hepatic metastasis, hepatocellular carcinoma and the hemangioma, probabily by the number of patients.
4. Conclusion
Diffusion-weighted MR imagin can help differentiate benign from malignant hepatic lesions.
Radiologists need to understand diffusion weigthted images when evaluantign lesions focal hepatics.
5. Personal Information
e-mail: pinarcis@yahoo.es
6. References
1.-Berman JI, Berger MS, Mukherjee P, Henry RG.. Diffusiontensor imaging-guided tracking of combined with intraoperative cortical stimulation mapping in patients with gliomas. J Neurosurg
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2.-Kim T,Murakami T, Takahashi S, Hori M, Tsuda K, Nakamura H. Diffusion-weighted single-shot echoplanar MR imaging for liver disease. AJR 1999; 173:393–398.
3.- Namimoto T, Yamashita Y, Sumi S, Tang Y, Takahashi M. Focal liver masses: characterization with diffusion-weighted echo-planar MR imaging. . Radiology 1997; 204:739–744
4.- Bruegel M, Holzapfel K, Gaa J, et al. Characterization of focal liver lesions by ADC measurement using a respiratory triggered diffusion-weighted sigle-shot echo-planar MR imaging technique. Eur
Radiol 2008;18(3):477-85. |
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